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OH is the most dangerous free radical and major culprit in free radicalmediated toxicity in cells.16, 3 Both O2 and OH can individually act on lipid membranes to promote the formation of lipid radical (L) which in the presence of oxygen is capable of generating lipid peroxy radical (LOO)3 (Fig

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Such an imbalance is responsible for severe damage to essential biomolecules, such as lipids (lipid peroxidation), proteins (oxidation and inactivation), and DNA (strand breakage and mutations), which is associated with the pathogenesis of numerous diseases, including cancer, neurodegenerative diseases, cardiovascular diseases, and the aging process [28]